Scans have confirmed Sharks prop Braden Hamlin-Uele suffered a knee cartilage injury in Saturday's win over the Rabbitohs.
Sharks medical staff are hopeful Hamlin-Uele will avoid surgery, with the Samoan international's return-to-play timeframe yet to be determined.
Meanwhile, bench forward Siosifa Talakai is rated a 50-50 chance to face the Bulldogs at Sharks Stadium on Saturday after recovering well from an ankle injury.
Talakai limped from the field in the 56th minute against South Sydney after being caught awkwardly in a tackle.
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